Guaiacol

Guaiacol
Names
	Preferred IUPAC name 2-Methoxyphenol
	Other names o-Methoxyphenol; O-Methylcatechol; 2-Hydroxyanisole; Pyroguaiac acid; Pyrocatechol monomethyl ether; 1-hydroxy-2-methoxybenzene
Identifiers
CAS Number	90-05-1 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:28591 ;
ChEMBL	ChEMBL13766 ;
ChemSpider	447 ;
ECHA InfoCard	100.001.786
KEGG	D00117 ;
PubChem CID	460;
UNII	6JKA7MAH9C ;
CompTox Dashboard (EPA)	DTXSID0023113 ;
	InChI InChI=1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3 Key: LHGVFZTZFXWLCP-UHFFFAOYSA-N ; InChI=1/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3 Key: LHGVFZTZFXWLCP-UHFFFAOYAI;
	SMILES COc1ccccc1O;
Properties
Chemical formula	C7H8O2
Molar mass	124.14 g/mol
Appearance	colorless oil or crystalline solid
Odor	Characteristic sweet odor
Density	1.112 g/cm3, liquid; 1.129 g/cm3, crystals
Melting point	26–29 °C (79–84 °F; 299–302 K)
Boiling point	204–206 °C (399–403 °F; 477–479 K)
Solubility in water	23.3 g/L (25 °C)
Solubility in carbon tetrachloride	Soluble
log P	1.32
Vapor pressure	0.103 mmHg (25 °C)
Henry's law; constant (kH)	1.2×10-6 atm-cu m/mol (25 °C)
Acidity (pKa)	9.98
Refractive index (nD)	1.5429 (20 °C)
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302, H315, H319
Precautionary statements	P264, P264+P265, P270, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, P501
Flash point	60 °C (140 °F; 333 K)
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	520 mg/kg (rat, oral); 170 mg/kg (mouse, intravenous); 4600 mg/kg (rabbit, skin)
LDLo (lowest published)	900 mg/kg (guinea pig, subcutaneous); 1250 mg/kg (rabbit, subcutaneous)
LC50 (median concentration)	7570 mg/m3 (mouse)
Related compounds
Related methoxyphenols	Mequinol; 3-Methoxyphenol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Guaiacol (/ˈɡwaɪəkɒl/) is an organic compound with the formula C₆H₄(OH)(OCH₃). It is a phenolic compound containing a methoxy functional group. Guaiacol appears as a viscous colorless oil, although aged or impure samples are often yellowish. It occurs widely in nature and is a common product of the pyrolysis of wood.