Growth hormone receptor

Ghr
Available structures
PDB	Human UniProt search: P16882 PDBe P16882 RCSB
List of PDB id codes
	1A22, 1AXI, 1HWG, 1HWH, 1KF9, 2AEW, 3HHR
Identifiers
Aliases	growth hormone receptorGHBPGHR/BP
External IDs	HomoloGene: 134; GeneCards: [1]; OMA:- orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	3,612,974 bp
RNA expression pattern
	Top expressed in
	proximal tubule; ; white adipose tissue; ; right kidney; ; left lobe of liver; ; human kidney; ; intercostal muscle; ; tunica adventitia of aorta; ; subcutaneous adipose tissue; ; ankle; ; sternocleidomastoid muscle;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein homodimerization activity; growth factor binding; peptide hormone binding; protein binding; cytokine receptor activity; proline-rich region binding; protein kinase binding; identical protein binding; growth hormone receptor activity; cytokine binding; protein phosphatase binding; SH2 domain binding;
Cellular component	integral component of membrane; membrane; receptor complex; integral component of plasma membrane; extracellular region; cell surface; growth hormone receptor complex; extracellular space; cytosol; plasma membrane; cytoplasmic ribonucleoprotein granule; external side of plasma membrane; extrinsic component of membrane; nucleus; cytoplasm; mitochondrion; soma;
Biological process	insulin-like growth factor receptor signaling pathway; receptor signaling pathway via JAK-STAT; growth hormone receptor signaling pathway via JAK-STAT; response to estradiol; endocytosis; allantoin metabolic process; regulation of multicellular organism growth; cytokine-mediated signaling pathway; citrate metabolic process; receptor internalization; response to cycloheximide; 2-oxoglutarate metabolic process; creatinine metabolic process; oxaloacetate metabolic process; fatty acid metabolic process; succinate metabolic process; cellular response to hormone stimulus; growth hormone receptor signaling pathway; taurine metabolic process; valine metabolic process; positive regulation of multicellular organism growth; positive regulation of peptidyl-tyrosine phosphorylation; creatine metabolic process; isoleucine metabolic process; positive regulation of tyrosine phosphorylation of STAT protein; activation of Janus kinase activity; hormone metabolic process; positive regulation of receptor signaling pathway via JAK-STAT; hormone-mediated signaling pathway; negative regulation of neuron death;
	Sources:Amigo / QuickGO
Orthologs
	14600
	n/a
	ENSMUSG00000055737
	n/a
	P10912
	n/a
	NM_001048147; NM_001048178; NM_010284; NM_001286370
	n/a
NP_000154; NP_001229328; NP_001229329; NP_001229330; NP_001229331;
	NP_001229332; NP_001229333; NP_001229334; NP_001229335; NP_001229389; NP_001229391; NP_001041643; NP_001273299; NP_034414
	n/a
	Wikidata
View/Edit Human

Growth hormone receptor is a protein that in humans is encoded by the GHR gene. GHR orthologs have been identified in most mammals.