Great Lakes Football Conference
| Conference | NCAA |
|---|---|
| Founded | 2006 |
| Ceased | 2011 |
| Commissioner | Bill Massoels |
| Sports fielded |
|
| Division | Division II |
| No. of teams | 6 (charter), 7 (total) |
| Headquarters | Rensselaer, Indiana |
| Region | Central United States |
The Great Lakes Football Conference (GLFC) was an American football-only conference that competed in NCAA Division II for six seasons (2006 through 2011). Bill Massoels, Athletic Director at St. Joseph's College, served as its commissioner, and the league was headquartered at the college in Rensselaer, Indiana. St. Joseph's was also the catalyst of a previous failed attempt to form a conference of the same name in the late 1990s.