Genomic organization

The hereditary material i.e. DNA (deoxyribonucleic acid) of an organism is composed of a sequence of four nucleotides in a specific pattern, which encodes information as a function of their order. Genomic organization refers to the linear order of DNA elements and their division into chromosomes. This organization is hierarchical, spanning from the linear molecular sequence (1D) to the folding of chromatin fibers to the spatial arrangement of chromosome territories within the nucleus. "Genome organization" can also refer to the 3D structure of chromosomes and the positioning of DNA sequences within the nucleus.

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