Gabamide

Gabamide
Clinical data
Other names	GABAmide; GABAMIDE; GABA amide; 4-Aminobutanamide; 4-ABAD; 4-Aminobutyramide; gamma-Aminobutyramide; γ-Aminobutyramide; GABAD; gamma-Aminobutyric acid amide; γ-Aminobutyric acid amide
Drug class	GABA receptor agonist
ATC code	None;
Identifiers
	IUPAC name 4-aminobutanamide;
CAS Number	3251-08-9;
PubChem CID	18615;
ChemSpider	17581;
UNII	DQN3YXP96S;
ChEMBL	ChEMBL1199935;
CompTox Dashboard (EPA)	DTXSID80186235 ;
ECHA InfoCard	100.019.852
Chemical and physical data
Formula	C4H10N2O
Molar mass	102.137 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C(CC(=O)N)CN;
	InChI InChI=1S/C4H10N2O/c5-3-1-2-4(6)7/h1-3,5H2,(H2,6,7); Key:WCVPFJVXEXJFLB-UHFFFAOYSA-N;

Gabamide, or GABAmide, also known as γ-aminobutyramide (GABAD), is a GABA receptor agonist and GABA analogue, or more specifically the amide of the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Along with GABA and progabide acid (SL-75.102), gabamide is an active metabolite of the anticonvulsant drug progabide (Gabrene; SL-76.002). Unlike progabide, but similarly to GABA, gabamide is unable to cross the blood–brain barrier and hence is peripherally selective. However, gabamide and GABA are formed in the brain from progabide following its entry into this part of the body.