GR-103545

GR-103545
Names
IUPAC name
methyl (3R)-4-[2-(3,4-dichlorophenyl)acetyl]-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate
Other names
GR-103545; 860VEX6583; GR103545
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C19H25Cl2N3O3/c1-27-19(26)23-8-9-24(15(13-23)12-22-6-2-3-7-22)18(25)11-14-4-5-16(20)17(21)10-14/h4-5,10,15H,2-3,6-9,11-13H2,1H3/t15-/m1/s1
    Key: HJUAKZYKCANOOZ-OAHLLOKOSA-N
  • OC(/C=C/C(O)=O)=O.ClC(C=C1CC(N2[C@@H](CN(CC2)C(OC)=O)CN3CCCC3)=O)=C(C=C1)Cl
Properties
C19H25Cl2N3O3
Molar mass 414.3 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

GR-103545 is a potent and highly selective κ-opioid receptor (KOR) agonist primarily employed as a radioligand in positron emission tomography (PET) neuroimaging research. When radiolabeled with carbon-11, [11C]GR-103545 serves as a neuroimaging tracer for quantifying KOR availability and receptor occupancy in the human brain.

This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.