GDF6

GDF6
Identifiers
Aliases	GDF6, BMP-13, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1, growth differentiation factor 6, SYNS4
External IDs	OMIM: 601147; MGI: 95689; HomoloGene: 40883; GeneCards: GDF6; OMA:GDF6 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	96,160,806 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	9,862,345 bp
RNA expression pattern
	Top expressed in
	placenta; ; gonad; ; ventricular zone; ; gallbladder; ; right auricle of heart; ; gastric mucosa; ; right coronary artery; ; Achilles tendon; ; smooth muscle tissue; ; left coronary artery;
	Top expressed in
	auditory ossicle; ; stapes; ; incus; ; malleus; ; ganglion; ; embryo; ; Jacobson's organ; ; sensory ganglion; ; genital tubercle; ; trigeminal ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	cytokine activity; protein homodimerization activity; transforming growth factor beta receptor binding; growth factor activity; protein binding;
Cellular component	extracellular region; extracellular space;
Biological process	regulation of apoptotic process; apoptotic process; pathway-restricted SMAD protein phosphorylation; retinal cell apoptotic process; regulation of MAPK cascade; cell development; positive regulation of pathway-restricted SMAD protein phosphorylation; BMP signaling pathway; positive regulation of transcription, DNA-templated; multicellular organism development; positive regulation of chondrocyte differentiation; positive regulation of neuron differentiation; activin receptor signaling pathway; SMAD protein signal transduction; positive regulation of p38MAPK cascade; fat cell differentiation; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	392255
	242316
	ENSG00000156466
	ENSMUSG00000051279
	Q6KF10
	P43028
	NM_001001557
	NM_013526
	NP_001001557
	NP_038554
	Wikidata
View/Edit Human	View/Edit Mouse

Growth differentiation factor 6 (GDF6) is a protein that in humans is encoded by the GDF6 gene.