Frizzled

For other uses, see Frizzle (disambiguation).
Frizzled/Smoothened family membrane region
Cartoon structure of the human protein Frizzled5, a member of the Frizzled protein family.
Identifiers
SymbolFrizzled
PfamPF01534
Pfam clanGPCR_A
InterProIPR000539
PROSITEPDOC50038
TCDB9.A.14
OPM superfamily6
OPM protein4jkv
CDDcd13951
Available protein structures:
PDB  IPR000539 PF01534 (ECOD; PDBsum)  
AlphaFold

Frizzled is a family of atypical G protein-coupled receptors that serve as receptors in the Wnt signaling pathway and other signaling pathways. There are 10 known Frizzled receptor family members in humans. When activated, Frizzled leads to activation of Dishevelled in the cytosol.

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