Fospropofol

Fospropofol
Chemical structure of fospropofol disodium
Clinical data
AHFS/Drugs.comMonograph
License data
Pregnancy
category
  • B
Dependence
liability
unknown
Routes of
administration
Intravenous
ATC code
Legal status
Legal status
Pharmacokinetic data
Protein binding98%
MetabolismHepatic glucuronidation
Elimination half-life0.81 hours
ExcretionRenal
Identifiers
  • disodium [2,6-di(propan-2-yl)phenoxy]methyl phosphate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H21O5P
Molar mass288.280 g·mol−1
3D model (JSmol)
  • CC(C)c1cccc(c1OCOP(=O)(O)O)C(C)C
  • InChI=1S/C13H21O5P/c1-9(2)11-6-5-7-12(10(3)4)13(11)17-8-18-19(14,15)16/h5-7,9-10H,8H2,1-4H3,(H2,14,15,16) N
  • Key:QVNNONOFASOXQV-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

Fospropofol (INN), often used as the disodium salt (trade name Lusedra), is an intravenous sedative-hypnotic agent. It is currently approved for use in sedation of adult patients undergoing diagnostic or therapeutic procedures such as endoscopy.