Sørensen formol titration

The Sørensen formol titration(SFT) invented by S. P. L. Sørensen in 1907 is a largely archaic method that was once used to determine the amino acid content of a sample. It is used in the determination of protein content in samples.

In case of tyrosine, the actual results are too high due to the negative hydroxyl group (-OH), which acts as a base. This explanation is supported by the fact that phenylalanine can be accurately titrated.

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