FCGR3A

FCGR3A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3AY4, 3SGJ, 3SGK, 3WN5, 5D6D, 5BW7
Identifiers
Aliases	FCGR3A, CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20, Fc fragment of IgG receptor IIIa, Fc gamma receptor IIIa, FcGRIIIA, CD16-II
External IDs	OMIM: 146740; MGI: 2179523; HomoloGene: 477; GeneCards: FCGR3A; OMA:FCGR3A - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	161,550,737 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	170,857,330 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; blood; ; spleen; ; appendix; ; placenta; ; right lung; ; upper lobe of left lung; ; C1 segment; ; left adrenal gland;
	Top expressed in
	granulocyte; ; ileum; ; jejunum; ; spleen; ; liver; ; ovary; ; secondary oocyte; ; bone marrow; ; adrenal gland; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	IgG binding;
Cellular component	integral component of membrane; extracellular region; plasma membrane; extracellular exosome; external side of plasma membrane; membrane;
Biological process	immune response; Fc-gamma receptor signaling pathway involved in phagocytosis; regulation of immune response;
	Sources:Amigo / QuickGO
Orthologs
	2214
	246256
	ENSG00000203747
	ENSMUSG00000059089
	P08637
	A0A0B4J1G0
NM_000569; NM_001127592; NM_001127593; NM_001127595; NM_001127596;
	NM_001329120; NM_001329122; NM_001386450
	NM_144559; NM_180961
NP_000560; NP_001121064; NP_001121065; NP_001121067; NP_001121068;
	NP_001316049; NP_001316051
	NP_653142
	Wikidata
View/Edit Human	View/Edit Mouse

Low affinity immunoglobulin gamma Fc region receptor III-A is a protein that in humans is encoded by the FCGR3A gene. It is also known as CD16a as it is part of the cluster of differentiation cell surface molecules.