Family-wise error rate

Family-wise error rate (FWER) is a term from statistics for the probability of making one or more false discoveries, or type I errors when performing multiple hypotheses tests. FWER is a metric that quantifies the risk caused by multiple testing. It's the probability of making one or more Type I errors across all tests in a family of comparisons. Controlling the FWER (for example, with Bonferroni or Holm corrections) is a way to address the problem created with multiple testing.