Fibrillarin

Available protein structures:
PDB	IPR000692 PF01269 (ECOD; PDBsum)
AlphaFold	IPR000692; PF01269;

Fibrillarin
Fibrillarin
	pyrococcus horikoshii fibrillarin pre-rrna processing protein
Identifiers
Symbol	Fibrillarin
Pfam	PF01269
Pfam clan	CL0063
InterPro	IPR000692
PROSITE	PDOC00489
SCOP2	1fbn / SCOPe / SUPFAM
PDB
Available protein structures:
PDB	IPR000692 PF01269 (ECOD; PDBsum)
AlphaFold	IPR000692; PF01269;

FBL
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2IPX
Identifiers
Aliases	FBL, FIB, FLRN, RNU3IP1, fibrillarin, Nop1
External IDs	OMIM: 134795; MGI: 95486; HomoloGene: 1099; GeneCards: FBL; OMA:FBL - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	39,846,379 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	27,878,694 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; left ovary; ; right ovary; ; skin of abdomen; ; skin of leg; ; canal of the cervix; ; ventricular zone; ; ectocervix; ; fallopian tube; ; monocyte;
	Top expressed in
	epiblast; ; yolk sac; ; bone marrow; ; lens; ; ventricular zone; ; lip; ; spleen; ; thymus; ; tail of embryo; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; rRNA methyltransferase activity; ATPase binding; histone-glutamine methyltransferase activity; protein binding; TFIID-class transcription factor complex binding; RNA binding;
Cellular component	small-subunit processome; Cajal body; membrane; nucleolus; dense fibrillar component; extracellular exosome; nucleus; box C/D RNP complex; granular component; chromosome; nucleoplasm; fibrillar center;
Biological process	tRNA processing; snoRNA localization; rRNA methylation; histone glutamine methylation; methylation; box C/D RNA 3'-end processing; sno(s)RNA metabolic process; osteoblast differentiation; rRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	2091
	14113
	ENSG00000105202; ENSG00000280548
	ENSMUSG00000046865
	P22087
	P35550
	NM_001436
	NM_007991
	NP_001427
	NP_032017
	Wikidata
View/Edit Human	View/Edit Mouse

rRNA 2'-O-methyltransferase fibrillarin is an enzyme that in humans is encoded by the FBL gene.