Etonitazene

Etonitazene
Clinical data
ATC code	none;
Legal status
Legal status	BR: Class A1 (Narcotic drugs); CA: Schedule I; DE: Anlage I (Authorized scientific use only); UK: Class A; US: Schedule I;
Identifiers
	IUPAC name 2-(p-Ethoxybenzyl)-1-diethylaminoethyl-5-nitrobenzimidazole;
CAS Number	911-65-9 ;
PubChem CID	13493;
IUPHAR/BPS	1624;
DrugBank	DB01462 ;
ChemSpider	12908 ;
UNII	9U3GT3353T;
KEGG	D12669 ;
ChEBI	CHEBI:234361;
ChEMBL	ChEMBL312040 ;
CompTox Dashboard (EPA)	DTXSID6048919 ;
ECHA InfoCard	100.011.827
Chemical and physical data
Formula	C22H28N4O3
Molar mass	396.491 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCOC1=CC=C(CC2=NC3=C(N2CCN(CC)CC)C=CC(N(=O)=O)=C3)C=C1;
	InChI InChI=1S/C22H28N4O3/c1-4-24(5-2)13-14-25-21-12-9-18(26(27)28)16-20(21)23-22(25)15-17-7-10-19(11-8-17)29-6-3/h7-12,16H,4-6,13-15H2,1-3H3 ; Key:PXDBZSCGSQSKST-UHFFFAOYSA-N ;
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Etonitazene, also known as EA-4941 or CS-4640, is a benzimidazole opioid, first reported in 1957, that has been shown to have approximately 1,000 to 1,500 times the potency of morphine in animals.

Because it is characterized by a strong dependency potential and a tendency to produce profound respiratory depression, it is not used in humans. It is, however, useful in animal models for addiction studies, particularly those requiring the animals to drink or ingest the agent, because it is not as bitter as opiate salts like morphine sulfate.