Estradiol valerate/norethisterone enantate

Estradiol valerate /
norethisterone enantate
Estradiol valerate (top) and
norethisterone enantate (bottom)
Combination of
Estradiol valerateEstrogen
Norethisterone enantateProgestogen
Clinical data
Trade namesMesigyna, others
Other namesEV/NETE; HRP-102
Routes of
administration		Intramuscular injection
Identifiers
CAS Number
PubChem CID
UNII

Estradiol valerate/norethisterone enantate (EV/NETE), sold under the brand name Mesigyna among others, is a form of combined injectable birth control which is used to prevent pregnancy in women. It contains estradiol valerate (EV), an estrogen, and norethisterone enantate (NETE), a progestin. The medication is given once a month by injection into muscle.

EV/NETE is approved for use in at least 36 countries, and is the most widely used combined injectable contraceptive. It is available widely throughout Latin America, in a few Asian and African countries, and in Turkey.

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