Epigenetic clock

An epigenetic clock is an analytical method used as a biomarker of aging to estimate "biological age." The method relies on age-related modifications to DNA that occur over time and regulate how genes are expressed. Many epigenetic clocks are based on the analysis of DNA methylation, measuring the accumulation of methyl groups to CpG regions of DNA molecules. More recently, new epigenetic clocks have been developed based on the histone code, chromatin accessibility and nucleosome positioning.

This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.