Ellipticine

Ellipticine
Names
Preferred IUPAC name
5,11-Dimethyl-6H-pyrido[4,3-b]carbazole
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.007.514
EC Number
  • 208-264-0
KEGG
UNII
  • InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3
  • CC1=C2C(=C(C3=C1C=CN=C3)C)C4=CC=CC=C4N2
Properties
C17H14N2
Molar mass 246.313 g·mol−1
Appearance Yellow crystalline powder
Density 1.257±0.06 g/cm3
Melting point 316–318 °C (601–604 °F; 589–591 K)
Very low
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 toxic
GHS labelling:
H301
P264, P270, P301+P310, P321, P330, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Ellipticine is a tetracyclic alkaloid first extracted from the tree species Ochrosia elliptica and Rauvolfia sandwicensis which inhibits the enzyme topoisomerase II via intercalative binding to DNA.

This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.