EXP-561

EXP-561
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name 4-phenylbicyclo[2.2.2]octan-1-amine;
CAS Number	10206-89-0 ; hydrochloride: 10207-08-6 ;
PubChem CID	27696;
ChemSpider	25769;
UNII	1P958G9T1V; hydrochloride: 6S9H885MKF ;
CompTox Dashboard (EPA)	DTXSID20144571 ;
Chemical and physical data
Formula	C14H19N
Molar mass	201.313 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES NC12CCC(CC1)(CC2)C3=CC=CC=C3;
	InChI InChI=1S/C14H19N.ClH/c15-14-9-6-13(7-10-14,8-11-14)12-4-2-1-3-5-12;/h1-5H,6-11,15H2;1H; Key:LTHJBDQSFIGMAZ-UHFFFAOYSA-N;

EXP-561 is an investigational drug that acts as an inhibitor of the reuptake of serotonin, dopamine, and norepinephrine. It was developed in the 1960s by Du Pont and was suggested as a potential antidepressant but failed in trials and was never marketed.

SAR simplification in the molecular structure leads to a compound called 4-Phenylcyclohexylamine [19992-45-1].