ETS2

ETS2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4BQA, 4MHV
Identifiers
Aliases	ETS2, ETS2IT1, ETS proto-oncogene 2, transcription factor
External IDs	OMIM: 164740; MGI: 95456; HomoloGene: 3838; GeneCards: ETS2; OMA:ETS2 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	38,824,955 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	95,522,095 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; mucosa of urinary bladder; ; skin of leg; ; gastric mucosa; ; rectum; ; spleen; ; upper lobe of left lung; ; ectocervix; ; olfactory zone of nasal mucosa; ; right lung;
	Top expressed in
	left lung lobe; ; tail of embryo; ; thymus; ; Paneth cell; ; granulocyte; ; skin of external ear; ; right lung; ; skin of back; ; conjunctival fornix; ; right lung lobe;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; glucocorticoid receptor binding; protein domain specific binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	plasma membrane; nucleoplasm; nucleus; cytosol;
Biological process	skeletal system development; cell differentiation; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription, DNA-templated; ectodermal cell fate commitment; mesoderm development; primitive streak formation; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	2114
	23872
	ENSG00000157557
	ENSMUSG00000022895
	P15036
	P15037
	NM_001256295; NM_005239
	NM_011809
	NP_001243224; NP_005230
	NP_035939
	Wikidata
View/Edit Human	View/Edit Mouse

ETS2 is a gene that in humans is encoding the C-ETS2 protein. The protein encoded by this gene belongs to the ETS family of transcription factors. It has been found to play a key role in the development of inflammatory bowel disease.