ETS1

ETS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1GVJ, 2NNY, 2STT, 2STW, 3MFK, 3RI4, 3WTS, 3WTT, 3WTU, 3WTV, 3WTW, 3WTX, 3WTY, 3WTZ, 3WU0, 3WU1, 4L0Y, 4L0Z, 4L18, 4LG0
Identifiers
Aliases	ETS1, ETS-1, EWSR2, p54, c-ets-1, ETS proto-oncogene 1, transcription factor
External IDs	OMIM: 164720; MGI: 95455; HomoloGene: 3837; GeneCards: ETS1; OMA:ETS1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	128,587,558 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	32,757,820 bp
RNA expression pattern
	Top expressed in
	visceral pleura; ; parietal pleura; ; tibia; ; epithelium of nasopharynx; ; lower lobe of lung; ; superficial temporal artery; ; epithelium of colon; ; pericardium; ; vena cava; ; lymph node;
	Top expressed in
	left lung lobe; ; thymus; ; mesenteric lymph nodes; ; blood; ; spleen; ; Gonadal ridge; ; right lung lobe; ; atrium; ; atrioventricular valve; ; endocardial cushion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; transcription factor binding; protein binding; identical protein binding; transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific double-stranded DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; histone acetyltransferase binding;
Cellular component	cytoplasm; transcription regulator complex; nucleoplasm; nucleus;
Biological process	regulation of apoptotic process; pituitary gland development; response to estradiol; response to interleukin-1; response to hypoxia; regulation of transcription, DNA-templated; positive regulation of erythrocyte differentiation; cell motility; estrous cycle; immune system process; regulation of transcription by RNA polymerase II; response to antibiotic; female pregnancy; angiogenesis involved in wound healing; positive regulation of cell migration; response to mechanical stimulus; response to laminar fluid shear stress; negative regulation of cell cycle; regulation of angiogenesis; transcription by RNA polymerase II; regulation of extracellular matrix disassembly; transcription, DNA-templated; positive regulation of endothelial cell migration; positive regulation of transcription, DNA-templated; PML body organization; response to wounding; immune response; positive regulation of cell population proliferation; hypothalamus development; negative regulation of inflammatory response; positive regulation of transcription by RNA polymerase II; negative regulation of cell population proliferation; cellular response to hydrogen peroxide; positive regulation of inflammatory response; pri-miRNA transcription by RNA polymerase II; positive regulation of leukocyte adhesion to vascular endothelial cell; positive regulation of gene expression; positive regulation of blood vessel endothelial cell migration; positive regulation of angiogenesis; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	2113
	23871
	ENSG00000134954
	ENSMUSG00000032035
	P14921
	P27577
	NM_001143820; NM_001162422; NM_005238; NM_001330451
	NM_001038642; NM_011808
	NP_001137292; NP_001155894; NP_001317380; NP_005229
NP_001033731; NP_035938; NP_001359463; NP_001359464; NP_001359465;
	NP_001359466
	Wikidata
View/Edit Human	View/Edit Mouse

Protein C-ets-1 is a protein that in humans is encoded by the ETS1 gene. The protein encoded by this gene belongs to the ETS family of transcription factors.