EPH receptor A3

EPHA3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2GSF, 2QO7, 2QO9, 2QOB, 2QOC, 2QOD, 2QOF, 2QOI, 2QOK, 2QOL, 2QON, 2QOO, 2QOQ, 3DZQ, 3FXX, 3FY2, 4G2F, 4GK2, 4GK3, 4GK4, 4L0P, 4P4C, 4P5Q, 4P5Z, 4TWN, 4TWO
Identifiers
Aliases	EPHA3, Epha3, AW492086, Cek4, ETK1, End3, Hek, Hek4, Mek4, Tyro4, EK4, ETK, EPH receptor A3, HEK, HEK4, TYRO4
External IDs	OMIM: 179611; MGI: 99612; HomoloGene: 21083; GeneCards: EPHA3; OMA:EPHA3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	89,482,134 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	63,684,538 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; buccal mucosa cell; ; urethra; ; gallbladder; ; mucosa of urinary bladder; ; tibia; ; Achilles tendon; ; prostate; ; right coronary artery; ; placenta;
	Top expressed in
	maxillary part of mouth; ; upper jaw; ; ganglionic eminence; ; tongue; ; calvaria; ; medial ganglionic eminence; ; human fetus; ; left lung lobe; ; efferent ductule; ; abdominal wall;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; GPI-linked ephrin receptor activity; kinase activity; protein binding; transmembrane receptor protein tyrosine kinase activity; protein tyrosine kinase activity; ATP binding; ephrin receptor activity; receptor tyrosine kinase; transmembrane signaling receptor activity; transmembrane-ephrin receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; extracellular region; early endosome; cytoplasm; neuron projection; receptor complex;
Biological process	cellular response to retinoic acid; regulation of actin cytoskeleton organization; fasciculation of motor neuron axon; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of GTPase activity; regulation of epithelial to mesenchymal transition; regulation of microtubule cytoskeleton organization; protein phosphorylation; cell adhesion; positive regulation of neuron projection development; regulation of focal adhesion assembly; fasciculation of sensory neuron axon; cell migration; ephrin receptor signaling pathway; peptidyl-tyrosine phosphorylation; negative regulation of endocytosis; positive regulation of protein localization to plasma membrane; negative regulation of signal transduction; cell differentiation; negative regulation of apoptotic process; positive regulation of ERK1 and ERK2 cascade; axon guidance;
	Sources:Amigo / QuickGO
Orthologs
	2042
	13837
	ENSG00000044524
	ENSMUSG00000052504
	P29320
	P29319; Q8BRB1
	NM_005233; NM_182644
	NM_010140; NM_001362452
	NP_005224; NP_872585
	NP_034270; NP_001349381
	Wikidata
View/Edit Human	View/Edit Mouse

EPH receptor A3 (ephrin type-A receptor 3) is a protein that in humans is encoded by the EPHA3 gene.