EIF5B

EIF5B
Identifiers
Aliases	EIF5B, IF2, eukaryotic translation initiation factor 5B
External IDs	OMIM: 606086; MGI: 2441772; HomoloGene: 134613; GeneCards: EIF5B; OMA:EIF5B - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	99,401,326 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	38,094,660 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; oocyte; ; secondary oocyte; ; internal globus pallidus; ; myocardium of left ventricle; ; gingival epithelium; ; pericardium; ; pars reticulata; ; cardia; ; external globus pallidus;
	Top expressed in
	tail of embryo; ; lens; ; genital tubercle; ; zygote; ; epithelium of lens; ; secondary oocyte; ; parotid gland; ; lacrimal gland; ; primary oocyte; ; epiblast;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; metal ion binding; GTP binding; hydrolase activity; translation initiation factor activity; RNA binding; GTPase activity;
Cellular component	cytosol; nucleus; cytoplasm;
Biological process	regulation of translational initiation; translational initiation; protein biosynthesis;
	Sources:Amigo / QuickGO
Orthologs
	9669
	226982
	ENSG00000158417
	ENSMUSG00000026083
	O60841
	Q05D44
	NM_015904
	NM_198303
	NP_056988
	NP_938045
	Wikidata
View/Edit Human	View/Edit Mouse

Eukaryotic translation initiation factor 5B is a protein that in humans is encoded by the EIF5B gene. eIF5B is homologous to the bacterial initiation factor 2, sharing a core structure while their involvement in translation initiation differs.