EF-Ts

EF-Ts, bacterial
Identifiers
SymbolEF-Ts/EF-1B
InterProIPR001816
Available protein structures:
PDB  IPR001816  
AlphaFold
EF-Ts dimerisation domain
Identifiers
SymbolEF_TS
PfamPF00889
InterProIPR014039
Available protein structures:
PDB  IPR014039 PF00889 (ECOD; PDBsum)  
AlphaFold

EF-Ts (elongation factor thermo stable) is one of the prokaryotic elongation factors. It is found in human mitochondria as TSFM. It is similar to eukaryotic EF-1B.

EF-Ts serves as the guanine nucleotide exchange factor for EF-Tu (elongation factor thermo unstable), catalyzing the release of guanosine diphosphate from EF-Tu. This enables EF-Tu to bind to a new guanosine triphosphate molecule, release EF-Ts, and go on to catalyze another aminoacyl tRNA addition.