Disulfide (biochemistry)

Disulfides (or disulphides in British English) commonly appear as post-translational modifications within proteins. The linkage is also called an SS-bond or sometimes a disulfide bridge and is usually derived from two thiol groups. Disulfide bridges formed between thiol groups in two cysteine residues are an important component of the tertiary and quaternary structure of proteins. They are similar to organic disulfides in their structure.