Diplocoria

Diplocoria
Other namesDouble pupil; two pupils in one iris; a subset of polycoria (when exactly two)
A case of diplocoria
SpecialtyOphthalmology
SymptomsGlare, photophobia, reduced contrast, monocular diplopia
ComplicationsAmblyopia (in childhood), visual discomfort
Usual onsetCongenital (rare) or acquired
CausesTrue accessory pupil with its own sphincter (very rare); more commonly, non-sphincter iris holes (pseudopolycoria) from surgery, trauma, or iris atrophy (e.g., ICE syndrome)
Diagnostic methodSlit-lamp examination, pharmacologic testing of pupillary reactivity, anterior-segment imaging
TreatmentTinted/prosthetic contact lens; surgical pupilloplasty in selected cases
FrequencyExtremely rare (mostly case reports)

Diplocoria is an ophthalmic term for the presence of two pupillary openings in a single iris ("double pupil"). In contemporary usage most reported "double pupils" represent pseudopolycoria: additional iris holes that lack their own sphincter muscle, whereas true diplocoria (a form of true polycoria) requires that each opening has a functional sphincter with synchronous constriction and dilation. The term derives from Greek diplo- ("double") and korē ("pupil").