Diphtheria toxin

tox diphtheria toxin precursor
Cartoon representation of the diphtheria toxin protein
Identifiers
OrganismCorynebacterium diphtheriae
Symboltox
Entrez2650491
RefSeq (Prot)NP_938615
UniProtP00587
Other data
EC number2.4.2.36
Chromosomegenome: 0.19 - 0.19 Mb
Search for
StructuresSwiss-model
DomainsInterPro
Diphtheria toxin, C domain
Identifiers
SymbolDiphtheria_C
PfamPF02763
Pfam clanCL0084
InterProIPR022406
SCOP21ddt / SCOPe / SUPFAM
TCDB1.C.7
Available protein structures:
PDB  IPR022406 PF02763 (ECOD; PDBsum)  
AlphaFold
Diphtheria toxin, T domain
Identifiers
SymbolDiphtheria_T
PfamPF02764
InterProIPR022405
SCOP21ddt / SCOPe / SUPFAM
TCDB1.C.7
Available protein structures:
PDB  IPR022405 PF02764 (ECOD; PDBsum)  
AlphaFold
Diphtheria toxin, R domain
Identifiers
SymbolDiphtheria_R
PfamPF01324
InterProIPR022404
SCOP21ddt / SCOPe / SUPFAM
TCDB1.C.7
Available protein structures:
PDB  IPR022404 PF01324 (ECOD; PDBsum)  
AlphaFold

Diphtheria toxin is an exotoxin secreted mainly by Corynebacterium diphtheriae (but also by Corynebacterium ulcerans and Corynebacterium pseudotuberculosis), the pathogenic bacterium that causes diphtheria. The toxin gene is encoded by a prophage called corynephage β. The toxin causes the disease in humans by gaining entry into the cell cytoplasm and inhibiting protein synthesis.


This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.