Dimetindene

Dimetindene
Clinical data
Trade names	Fenistil
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral, topical
ATC code	D04AA13 (WHO) R06AB03 (WHO);
Legal status
Legal status	AU: S4 (Prescription only); UK: General sales list (GSL, OTC);
Identifiers
	IUPAC name N,N-Dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethan-1-amine;
CAS Number	5636-83-9 3614-69-5;
PubChem CID	21855;
DrugBank	DB08801 ;
ChemSpider	20541 ;
UNII	661FH77Z3P;
KEGG	D07853 ;
ChEMBL	ChEMBL22108 ;
CompTox Dashboard (EPA)	DTXSID9022942 ;
ECHA InfoCard	100.024.622
Chemical and physical data
Formula	C20H24N2
Molar mass	292.426 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES n1ccccc1C(C=3c2ccccc2CC=3CCN(C)C)C;
	InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3 ; Key:MVMQESMQSYOVGV-UHFFFAOYSA-N ;
	(verify)

Dimetindene, also sold under the brand name Fenistil, is an antihistamine/anticholinergic. It is a first generation selective H1 antagonist. Dimetindene is an atypical first generation H1 antagonist as it only minimally passes across the blood–brain barrier.

Dimetindene is also an M2 receptor antagonist.

It was patented in 1958 and came into medical use in 1960.