Delta-like 1

DLL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4XBM
Identifiers
Aliases	DLL1, DELTA1, DL1, Delta, Delta-like 1, delta like canonical Notch ligand 1, NEDBAS
External IDs	OMIM: 606582; MGI: 104659; HomoloGene: 4104; GeneCards: DLL1; OMA:DLL1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	170,306,565 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	15,597,134 bp
RNA expression pattern
	Top expressed in
	spleen; ; ventricular zone; ; skin of abdomen; ; skin of leg; ; prostate; ; apex of heart; ; mucosa of esophagus; ; vagina; ; right auricle of heart; ; minor salivary glands;
	Top expressed in
	paraxial mesoderm; ; tail of embryo; ; ventricular zone; ; primitive streak; ; ciliary body; ; tongue muscle; ; corneal stroma; ; ganglionic eminence; ; medial ganglionic eminence; ; right lung;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; scaffold protein binding; Tat protein binding; Notch binding; protein binding;
Cellular component	integral component of membrane; membrane; adherens junction; plasma membrane; integral component of plasma membrane; extracellular region; cell junction; apical plasma membrane; membrane raft; cytoplasmic vesicle;
Biological process	Notch signaling pathway; somitogenesis; negative regulation of interleukin-10 production; proximal/distal pattern formation; cell differentiation; negative regulation of myoblast differentiation; organ growth; regulation of somitogenesis; regulation of cell division; negative regulation of neuron differentiation; loop of Henle development; negative regulation of inner ear auditory receptor cell differentiation; astrocyte development; somite specification; negative regulation of glial cell apoptotic process; negative regulation of cell differentiation; neuron fate specification; endothelial tip cell fate specification; cell-cell signaling; regulation of skeletal muscle tissue growth; marginal zone B cell differentiation; skeletal muscle tissue growth; lateral inhibition; regulation of vascular endothelial growth factor signaling pathway; neuronal stem cell population maintenance; positive regulation of sprouting angiogenesis; regulation of blood pressure; heart looping; cerebellar molecular layer formation; cell communication; positive regulation of endocytosis; retina morphogenesis in camera-type eye; proximal tubule development; negative regulation of epidermal cell differentiation; clathrin-dependent endocytosis; determination of left/right symmetry; regulation of cell adhesion; cerebellar Purkinje cell layer structural organization; compartment pattern specification; positive regulation of gene expression; retina development in camera-type eye; skin epidermis development; positive regulation of cell population proliferation; nephron development; spinal cord development; cell fate determination; inner ear development; multicellular organism development; regulation of growth; Notch signaling pathway involved in arterial endothelial cell fate commitment; type B pancreatic cell development; negative regulation of epithelial cell differentiation; negative regulation of myeloid cell differentiation; positive regulation of skeletal muscle tissue growth; regulation of neurogenesis; left/right axis specification; positive regulation of Notch signaling pathway; negative regulation of cell population proliferation; positive regulation of transcription by RNA polymerase II; negative regulation of cardiac muscle cell differentiation; hemopoiesis; energy homeostasis;
	Sources:Amigo / QuickGO
Orthologs
	28514
	13388
	ENSG00000275555; ENSG00000198719
	ENSMUSG00000014773
	O00548
	Q61483
	NM_005618
	NM_007865; NM_001379042
	NP_005609
	NP_031891; NP_001365971
	Wikidata
View/Edit Human	View/Edit Mouse

Delta-like protein 1 is a protein that in humans is encoded by the DLL1 gene.