DYNLL1

DYNLL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1CMI, 3ZKE, 3ZKF, 1F95, 1F3C, 1F96
Identifiers
Aliases	DYNLL1, DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, PIN, hdlc1, dynein light chain LC8-type 1
External IDs	OMIM: 601562; MGI: 1861457; HomoloGene: 133063; GeneCards: DYNLL1; OMA:DYNLL1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	120,498,493 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	115,439,058 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; frontal pole; ; gingival epithelium; ; cingulate gyrus; ; anterior cingulate cortex; ; Brodmann area 9; ; bronchial epithelial cell; ; right testis; ; Brodmann area 10; ; right frontal lobe;
	Top expressed in
	medial ganglionic eminence; ; endocardial cushion; ; dentate gyrus of hippocampal formation granule cell; ; maxillary prominence; ; condyle; ; mandibular prominence; ; spermatid; ; hair follicle; ; seminiferous tubule; ; abdominal wall;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein domain specific binding; protein C-terminus binding; protein binding; cytoskeletal motor activity; cytoskeletal protein binding; plus-end-directed microtubule motor activity; dynein intermediate chain binding; dynein light intermediate chain binding; enzyme binding; nitric-oxide synthase regulator activity; protein homodimerization activity; protein heterodimerization activity; scaffold protein binding;
Cellular component	cytoplasm; cytosol; centrosome; membrane; plasma membrane; microtubule associated complex; ciliary tip; mitochondrion; dynein complex; COP9 signalosome; mitotic spindle; microtubule; cytoskeleton; extracellular exosome; nucleus; kinetochore; cytoplasmic dynein complex; cilium; tertiary granule membrane; ficolin-1-rich granule membrane; microtubule organizing center; secretory granule; axon cytoplasm;
Biological process	regulation of transcription, DNA-templated; substantia nigra development; antigen processing and presentation of exogenous peptide antigen via MHC class II; transcription, DNA-templated; endoplasmic reticulum to Golgi vesicle-mediated transport; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; G2/M transition of mitotic cell cycle; microtubule-based process; intraciliary retrograde transport; viral process; negative regulation of phosphorylation; macroautophagy; apoptotic process; intraciliary transport involved in cilium assembly; neutrophil degranulation; motile cilium assembly; ciliary basal body-plasma membrane docking; positive regulation of non-motile cilium assembly; transport along microtubule; cilium assembly; sister chromatid cohesion; regulation of G2/M transition of mitotic cell cycle; transport; spermatid development; positive regulation of insulin secretion involved in cellular response to glucose stimulus;
	Sources:Amigo / QuickGO
Orthologs
	8655
	56455
	ENSG00000088986
	ENSMUSG00000009013
	P63167
	P63168
	NM_003746; NM_001037494; NM_001037495
	NM_019682
	NP_001032583; NP_001032584; NP_003737
	NP_062656
	Wikidata
View/Edit Human	View/Edit Mouse

Dynein light chain 1, cytoplasmic is a protein that in humans is encoded by the DYNLL1 gene.