Congenital diaphragmatic hernia

Congenital diaphragmatic hernia
Other namesCDH
Chest radiograph showing a right-sided congenital diaphragmatic hernia in a neonate, with visible bowel loops in the thoracic cavity
SpecialtyPediatrics, medical genetics
SymptomsRespiratory distress at birth
Usual onsetCongenital
TypesBochdalek hernia, Morgagni hernia
CausesAbnormal development of the diaphragm
Diagnostic methodPrenatal ultrasound, chest radiography
TreatmentRespiratory support, surgical repair
PrognosisVariable; depends on severity and associated anomalies
Frequency2–3 per 10,000 live births

Congenital diaphragmatic hernia (CDH) is a birth defect of the diaphragm. The most common type of CDH is a Bochdalek hernia; other types include Morgagni hernia, diaphragm eventration and central tendon defects of the diaphragm. Malformation of the diaphragm allows the abdominal organs to push into the chest cavity, hindering proper lung formation.

CDH is a life-threatening condition in infants and a major cause of death due to two complications: pulmonary hypoplasia and pulmonary hypertension. Experts disagree on the relative importance of these two conditions, with some focusing on hypoplasia, others on hypertension. Newborns with CDH often have severe respiratory distress which can be life-threatening unless treated appropriately.