Columbamine

Columbamine
Names
	IUPAC name 3,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol
	Other names Dehydroisocorypalmine
Identifiers
CAS Number	3621-36-1 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:15920;
ChEMBL	ChEMBL400345;
ChemSpider	65261;
KEGG	C01795;
PubChem CID	72310;
UNII	7T4808FEJW;
CompTox Dashboard (EPA)	DTXSID80189766 ;
	InChI InChI=1S/C20H19NO4/c1-23-18-5-4-12-8-16-14-10-17(22)19(24-2)9-13(14)6-7-21(16)11-15(12)20(18)25-3/h4-5,8-11H,6-7H2,1-3H3/p+1 Key: YYFOFDHQVIODOQ-UHFFFAOYSA-O;
	SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)O)OC;
Properties
Chemical formula	C20H20NO4+
Molar mass	338.382 g·mol−1
Melting point	280–282 °C (536–540 °F; 553–555 K) (chloride salt)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Columbamine is an isoquinoline alkaloid made up of four rings, two of which contain nitrogen. It is related to berberine but without its methylenedioxy group. Columbamine is also called dehydroisocorypalmine. It has usually been isolated and characterised as its chloride salt.