Church of St. Ignatius Loyola (New York City)

The Church of St. Ignatius Loyola (also referred to as the Church of St. Ignatius of Loyola) is a Roman Catholic parish church on the Upper East Side of Manhattan in New York City. Administered by the Society of Jesus, the parish falls under the authority of the Roman Catholic Archdiocese of New York. It was established in 1851 as St. Lawrence O'Toole's Church. In 1898, Rome granted permission to change the patron saint to St. Ignatius of Loyola, the founder of the Jesuit order.

The church is located at 980 Park Avenue, on the southwest corner of Park Avenue and East 84th Street. It forms the centerpiece of a large Jesuit complex occupying most of the block bounded by Park Avenue, East 83rd Street, Lexington Avenue, and East 84th Street. The complex includes Wallace Hall (the parish hall beneath the church), the rectory on Park Avenue, and the Saint Ignatius Loyola School (the parish grammar school) directly behind the church. The complex is also home to two Jesuit high schools: Loyola School (a coeducational college-preparatory school) and Regis High School (an all-scholarship, merit-based, boys' college-preparatory school).

The church was designated a New York City Landmark on March 4, 1969, and was added to the National Register of Historic Places on July 24, 1980.