Chloroacetaldehyde

Chloroacetaldehyde
Names
	Preferred IUPAC name Chloroacetaldehyde
	Systematic IUPAC name Chloroethanal
	Other names 2-Chloroacetaldehyde; 2-Chloroethanal
Identifiers
CAS Number	107-20-0 ; 34789-09-8 (hydrate) ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:27871;
ChemSpider	32 ;
ECHA InfoCard	100.003.158
EC Number	203-472-8;
PubChem CID	33;
UNII	CF069F5D9C ; 61S63ROQ1E (hydrate) ;
CompTox Dashboard (EPA)	DTXSID4020292 ;
	InChI InChI=1S/C2H3ClO/c3-1-2-4/h2H,1H2 Key: QSKPIOLLBIHNAC-UHFFFAOYSA-N;
	SMILES C(C=O)Cl;
Properties
Chemical formula	C2H3ClO
Molar mass	78.50 g mol−1
Appearance	Colourless liquid
Odor	acrid, penetrating
Density	1.117 g/mL
Melting point	−16.3 °C (2.7 °F; 256.8 K) hydrate melts at 43–50 °C
Boiling point	85 to 85.5 °C (185.0 to 185.9 °F; 358.1 to 358.6 K)
Solubility in water	soluble
Solubility	organic solvents
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	alkylating agent
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H301, H311, H314, H330, H351, H400
Flash point	87.7 °C (189.9 °F) (closed cup)
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	89 mg/kg (oral, rat); 82 mg/kg (oral, mouse)
LC50 (median concentration)	200 ppm (rat, 1 hr)
	NIOSH (US health exposure limits):
PEL (Permissible)	C 1 ppm (3 mg/m3)
REL (Recommended)	C 1 ppm (3 mg/m3)
IDLH (Immediate danger)	45 ppm
Related compounds
Related compounds	2-chloroethanol, Chloroacetic acid
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Chloroacetaldehyde is an organic compound with the formula ClCH₂CHO. Like some related compounds, it is highly electrophilic reagent and a potentially dangerous alkylating agent. The compound is not normally encountered in the anhydrous form, but rather as the hemiacetal (ClCH₂CH(OH))₂O.

Chloroacetaldehyde is a metabolite of the antineoplastic ifosfamide and believed to be responsible for some of the toxicity observed with ifosfamide.