CRABP2

CRABP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1BLR, 1BM5, 1CBQ, 1CBS, 1XCA, 2CBS, 2FR3, 2FRS, 2FS6, 2FS7, 2G78, 2G79, 2G7B, 3CBS, 3CR6, 3CWK, 3D95, 3D96, 3D97, 3F8A, 3F9D, 3FA6, 3FA7, 3FA8, 3FA9, 3FEK, 3FEL, 3FEN, 3FEP, 3I17, 4I9R, 4I9S, 4M6S, 4M7M, 4QGV, 4QGW, 4QGX, 4YBP, 4YBU, 4YKM, 4YKO, 4YCH, 4YGZ, 4YFP, 4YFQ, 4YGH, 4YH0, 4YFR, 4YCE, 4YGG, 4YDA, 4YDB, 5HZQ
Identifiers
Aliases	CRABP2, CRABP-II, RBP6, cellular retinoic acid binding protein 2
External IDs	OMIM: 180231; MGI: 88491; HomoloGene: 1415; GeneCards: CRABP2; OMA:CRABP2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	156,705,816 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	87,860,683 bp
RNA expression pattern
	Top expressed in
	gums; ; gingival epithelium; ; vulva; ; oral cavity; ; skin of abdomen; ; mucosa of pharynx; ; skin of limb; ; skin of leg; ; skin of arm; ; vagina;
	Top expressed in
	somite; ; maxillary prominence; ; hand; ; neural ectoderm; ; mandibular prominence; ; otic placode; ; esophagus; ; lip; ; otic vesicle; ; primitive streak;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transporter activity; lipid binding; retinol binding; retinoic acid binding; protein binding; retinal binding; retinoid binding;
Cellular component	extracellular exosome; endoplasmic reticulum; nucleus; nucleoplasm; cytoplasm; cytosol;
Biological process	regulation of transcription, DNA-templated; positive regulation of collateral sprouting; retinoic acid metabolic process; embryonic forelimb morphogenesis; signal transduction; regulation of retinoic acid receptor signaling pathway; epidermis development; retinoic acid biosynthetic process; transport;
	Sources:Amigo / QuickGO
Orthologs
	1382
	12904
	ENSG00000143320
	ENSMUSG00000004885
	P29373
	P22935
	NM_001878; NM_001199723
	NM_007759
	NP_001186652; NP_001869
	NP_031785
	Wikidata
View/Edit Human	View/Edit Mouse

Cellular retinoic acid-binding protein 2 is a cytoplasmic binding protein that in humans is encoded by the CRABP2 gene.

CRABP2 is structurally similar to CRABP1, but CRABP2 has a lower affinity for retinoic acid (RA). CRABP2 is associated with cells that produce large amounts of retinoic acid and may play a role in mediating the effects of retinoic acid in the cell.