CMKLR2

CMKLR2
Identifiers
Aliases	CMKLR2, G protein-coupled receptor 1, chemerin chemokine-like receptor 2, GPR1
External IDs	OMIM: 600239; MGI: 2385324; HomoloGene: 21094; GeneCards: CMKLR2; OMA:CMKLR2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	206,218,047 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	63,253,702 bp
RNA expression pattern
	Top expressed in
	placenta; ; stromal cell of endometrium; ; testicle; ; mucosa of esophagus; ; skin of leg; ; right adrenal cortex; ; ventricular zone; ; left adrenal gland; ; gallbladder; ; left adrenal cortex;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; zygote; ; placenta; ; urethra; ; female urethra; ; decidua; ; male urethra; ; epithelium of urethra; ; epithelium of male urethra;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	neuropeptide binding; signal transducer activity; protein binding; G protein-coupled receptor activity; peptide binding;
Cellular component	membrane; integral component of membrane; integral component of plasma membrane; neuron projection; plasma membrane; intracellular membrane-bounded organelle; nucleoplasm;
Biological process	chemical synaptic transmission; neuropeptide signaling pathway; G protein-coupled receptor signaling pathway; signal transduction; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;
	Sources:Amigo / QuickGO
Orthologs
	2825
	241070
	ENSG00000183671; ENSG00000283448
	ENSMUSG00000046856
	P46091
	Q8K087
NM_001098199; NM_001261452; NM_001261453; NM_001261454; NM_001261455;
	NM_005279; NM_001389445
	NM_146250; NM_001357045
NP_001091669; NP_001248381; NP_001248382; NP_001248383; NP_001248384;
	NP_005270
	NP_666362; NP_001343974
	Wikidata
View/Edit Human	View/Edit Mouse

Chemerin-like receptor 2, is a protein that in humans is encoded by the CMKLR2 gene.

CMKLR2 is a rhodopsin-like receptor and therefore a member of the G protein-coupled receptor family of transmembrane receptors. It functions as a receptor for chemerin. Other receptors for chemerin include CMKLR1 and CCRL2.