CHMP4B

CHMP4B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3C3Q, 3UM3, 4ABM
Identifiers
Aliases	CHMP4B, C20orf178, CHMP4A, CTPP3, CTRCT31, SNF7, SNF7-2, Shax1, VPS32B, Vps32-2, dJ553F4.4, charged multivesicular body protein 4B
External IDs	OMIM: 610897; MGI: 1922858; HomoloGene: 57102; GeneCards: CHMP4B; OMA:CHMP4B - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	33,854,366 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	154,536,705 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; skin of arm; ; tibialis anterior muscle; ; nasal epithelium; ; mucosa of transverse colon; ; cartilage tissue; ; cardiac muscle tissue of right atrium; ; muscle layer of sigmoid colon; ; gastric mucosa; ; tibial arteries;
	Top expressed in
	vestibular membrane of cochlear duct; ; Ileal epithelium; ; Epithelium of choroid plexus; ; transitional epithelium of urinary bladder; ; conjunctival fornix; ; substantia nigra; ; facial motor nucleus; ; anterior horn of spinal cord; ; iris; ; motor neuron;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; protein binding; identical protein binding; cadherin binding;
Cellular component	cytoplasm; ESCRT III complex; cytosol; endosome; membrane; late endosome membrane; cytoplasmic side of plasma membrane; membrane coat; extracellular exosome; vesicle; midbody; nuclear envelope; nucleus;
Biological process	negative regulation of autophagosome assembly; regulation of centrosome duplication; viral life cycle; nucleus organization; maintenance of lens transparency; multivesicular body assembly; negative regulation of cell death; regulation of mitotic spindle assembly; autophagy; endosomal transport; posttranslational protein targeting to endoplasmic reticulum membrane; ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway; protein transport; septum digestion after cytokinesis; mitotic metaphase plate congression; protein homooligomerization; vacuolar transport; negative regulation of neuron death; nuclear membrane reassembly; exit from mitosis; mitotic cytokinesis; regulation of autophagy; membrane fission; macroautophagy; transport; viral budding via host ESCRT complex; midbody abscission;
	Sources:Amigo / QuickGO
Orthologs
	128866
	75608
	ENSG00000101421
	ENSMUSG00000038467
	Q9H444
	Q9D8B3
	NM_176812
	NM_029362
	NP_789782
	NP_083638
	Wikidata
View/Edit Human	View/Edit Mouse

Charged multivesicular body protein 4b is a protein that in humans is encoded by the CHMP4B gene.