Caspase 7

CASP7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1F1J, 1GQF, 1I4O, 1I51, 1K86, 1K88, 1KMC, 1SHJ, 1SHL, 2QL5, 2QL7, 2QL9, 2QLB, 2QLF, 2QLJ, 3EDR, 3H1P, 3IBC, 3IBF, 3R5K, 4FDL, 4FEA, 4HQ0, 4HQR, 4JB8, 4JJ8, 4JR1, 4JR2, 4LSZ, 4ZVR, 4ZVQ, 4ZVO, 4ZVU, 4ZVT, 4ZVS, 4ZVP, 5IC6
Identifiers
Aliases	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3, Caspase 7
External IDs	OMIM: 601761; MGI: 109383; HomoloGene: 11168; GeneCards: CASP7; OMA:CASP7 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	113,730,907 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	56,430,776 bp
RNA expression pattern
	Top expressed in
	rectum; ; palpebral conjunctiva; ; epithelium of nasopharynx; ; jejunal mucosa; ; mucosa of transverse colon; ; duodenum; ; parotid gland; ; nasal epithelium; ; mucosa of sigmoid colon; ; mucosa of paranasal sinus;
	Top expressed in
	intestinal villus; ; Ileal epithelium; ; jejunum; ; lens; ; left colon; ; duodenum; ; submandibular gland; ; pineal gland; ; conjunctival fornix; ; choroidal fissure;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cysteine-type peptidase activity; cysteine-type endopeptidase activity; protein binding; hydrolase activity; peptidase activity; cysteine-type endopeptidase activity involved in execution phase of apoptosis; cysteine-type endopeptidase activity involved in apoptotic process;
Cellular component	cytoplasm; cytosol; nucleus; nucleoplasm;
Biological process	proteolysis; cellular response to staurosporine; execution phase of apoptosis; apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	840
	12369
	ENSG00000165806
	ENSMUSG00000025076
	P55210
	P97864
NM_001227; NM_001267056; NM_001267057; NM_001267058; NM_033338;
	NM_033339; NM_033340; NM_001320911
	NM_007611
NP_001218; NP_001253985; NP_001253986; NP_001253987; NP_001307840;
	NP_203124; NP_203125; NP_203126
	NP_031637
	Wikidata
View/Edit Human	View/Edit Mouse

Caspase-7, apoptosis-related cysteine peptidase, also known as CASP7, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. Unique orthologs are also present in birds, lizards, lissamphibians, and teleosts.