Rimexolone

Rimexolone
Clinical data
Trade names	Vexol
Other names	Trimexolone; Org 6216; 11β-Hydroxy-16α,17α,21-trimethylpregna-1,4-dien-3,20-dione
AHFS/Drugs.com	Monograph
MedlinePlus	a606003
Routes of; administration	Eye drops
ATC code	H02AB12 (WHO) S01BA13 (WHO);
Pharmacokinetic data
Elimination half-life	estimated 1–2 hours
Excretion	>80% faeces
Identifiers
	IUPAC name (8S,9S,10R,11S,13S,14S,16R,17S)-11-Hydroxy-10,13,16,17-tetramethyl-17-propanoyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one;
CAS Number	49697-38-3 ;
PubChem CID	5311412;
IUPHAR/BPS	7099;
DrugBank	DB00896 ;
ChemSpider	4470902 ;
UNII	O7M2E4264D;
KEGG	D05729 ;
ChEMBL	ChEMBL1200617 ;
CompTox Dashboard (EPA)	DTXSID4045474 ;
ECHA InfoCard	100.211.227
Chemical and physical data
Formula	C24H34O3
Molar mass	370.533 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(=O)[C@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C)C)C;
	InChI InChI=1S/C24H34O3/c1-6-20(27)24(5)14(2)11-18-17-8-7-15-12-16(25)9-10-22(15,3)21(17)19(26)13-23(18,24)4/h9-10,12,14,17-19,21,26H,6-8,11,13H2,1-5H3/t14-,17+,18+,19+,21-,22+,23+,24-/m1/s1 ; Key:QTTRZHGPGKRAFB-OOKHYKNYSA-N ;
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Rimexolone is a glucocorticoid steroid used to treat inflammation in the eye. It is marketed as a 1% eye drop suspension under the trade name Vexol by Alcon Laboratories, but was discontinued in the US and other countries.