Anecortave acetate

Anecortave acetate
Clinical data
Other names	δ9(11)-11-Deoxycortisol 21-acetate; 17α,21-Dihydroxy-δ9(11)-progesterone 21-acetate; 17α,21-Dihydroxypregna-4,9(11)-diene-3,20-dione 21-acetate
AHFS/Drugs.com	International Drug Names
Routes of; administration	intravitreal depot injection
ATC code	S01LA02 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only);
Identifiers
	IUPAC name [2-[(8R,10S,13S,14R,17R)-; 17-hydroxy-10,13-dimethyl-3-oxo-; 2,6,7,8,12,14,15,16-octahydro-; 1H-cyclopenta[a]phenanthren-17-yl]-; 2-oxo-ethyl] acetate;
CAS Number	7753-60-8 ;
PubChem CID	111332;
PubChem SID	175426966;
DrugBank	DB05288 ;
ChemSpider	99892 ;
UNII	Y0PC411K4T;
KEGG	D01733;
ChEBI	CHEBI:31215;
ChEMBL	ChEMBL2106613 ;
CompTox Dashboard (EPA)	DTXSID5046805 ;
ECHA InfoCard	100.028.920
Chemical and physical data
Formula	C23H30O5
Molar mass	386.488 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OCC(=O)[C@@]1(O)CC[C@H]2[C@H]4/C(=C\C[C@]12C)[C@@]3(/C(=C\C(=O)CC3)CC4)C)C;
	InChI InChI=1S/C23H30O5/c1-14(24)28-13-20(26)23(27)11-8-19-17-5-4-15-12-16(25)6-9-21(15,2)18(17)7-10-22(19,23)3/h7,12,17,19,27H,4-6,8-11,13H2,1-3H3/t17-,19+,21+,22+,23+/m1/s1 ; Key:YUWPMEXLKGOSBF-GACAOOTBSA-N ;
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Anecortave (rINN) /ænəˈkɔːrteɪv/ is a novel angiogenesis inhibitor used in the treatment of the exudative (wet) form of age-related macular degeneration. Although similar in chemical structure to the corticosteroid hydrocortisone acetate, it possesses no glucocorticoid activity. If it is approved, it will be marketed by Alcon as anecortave acetate for depot suspension under the trade name Retaane. No development has been reported since 2010.