Descarboxylysergic acid

Descarboxylysergic acid
Clinical data
Other names	8-Descarboxylysergic acid; Descarboxyllysergic acid; DCLA; 9,10-Didehydro-6-methylergoline; 6-Methyl-9,10-didehydroergoline; 6-Methyl-9-ergolene
Drug class	Simplified/partial LSD analogue
Identifiers
	IUPAC name (6aR)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline;
CAS Number	51867-17-5;
PubChem CID	191210;
ChemSpider	166049;
CompTox Dashboard (EPA)	DTXSID00966197 ;
Chemical and physical data
Formula	C15H16N2
Molar mass	224.307 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCC=C2[C@H]1CC3=CNC4=CC=CC2=C34;
	InChI InChI=1S/C15H16N2/c1-17-7-3-5-11-12-4-2-6-13-15(12)10(9-16-13)8-14(11)17/h2,4-6,9,14,16H,3,7-8H2,1H3/t14-/m1/s1; Key:AHFZNJIKXMBLTJ-CQSZACIVSA-N;

Descarboxylysergic acid (DCLA), or 8-descarboxylysergic acid, also known as 9,10-didehydro-6-methylergoline or as 6-methyl-9-ergolene, is a drug of the ergoline and partial lysergamide families related to lysergic acid and lysergamides like lysergic acid diethylamide (LSD). It is the analogue of lysergic acid in which the carboxyl group at the C8 position of the molecule has been removed. DCLA was synthesized in an attempt to help elucidate the minimum structural requirements for biological activity of ergoline and lysergamide drugs like LSD.