Biricodar

Biricodar
Clinical data
ATC code	none;
Identifiers
	IUPAC name 1,7-di(pyridin-3-yl)heptan-4-yl (2S)-1-[oxo(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate;
CAS Number	174254-13-8 ;
PubChem CID	3037617;
ChemSpider	2301309 ;
UNII	9WQP0L619L;
ChEMBL	ChEMBL350775 ;
CompTox Dashboard (EPA)	DTXSID50893944 ;
Chemical and physical data
Formula	C34H41N3O7
Molar mass	603.716 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(C(=O)c1cc(OC)c(OC)c(OC)c1)N4[C@H](C(=O)OC(CCCc2cccnc2)CCCc3cccnc3)CCCC4;
	InChI InChI=1S/C34H41N3O7/c1-41-29-20-26(21-30(42-2)32(29)43-3)31(38)33(39)37-19-5-4-16-28(37)34(40)44-27(14-6-10-24-12-8-17-35-22-24)15-7-11-25-13-9-18-36-23-25/h8-9,12-13,17-18,20-23,27-28H,4-7,10-11,14-16,19H2,1-3H3/t28-/m0/s1 ; Key:CGVWPQOFHSAKRR-NDEPHWFRSA-N ;
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Biricodar (INN, codename VX-710, brand name Incel) was a pharmaceutical drug under development by Vertex Pharmaceuticals to help treat antineoplastic resistance in cancer.

Biricodar is considered a second-generation ABC transporter inhibitor and has been described as one of the most famous foundational drugs of this class. Although it has not been brought to market, biricodar continues to be used in basic research and is a compound of interest for potential clinical applications.