Big Brain Academy: Brain vs. Brain

Big Brain Academy: Brain vs. Brain is a 2021 party, puzzle, and edutainment video game developed by Nintendo EPD and published by Nintendo. The game released on December 3, 2021 for the Nintendo Switch. It is the third entry in the Big Brain Academy series, following the release of Big Brain Academy (2005) and Big Brain Academy: Wii Degree (2007) over a decade later. In Big Brain Academy: Brain vs. Brain, the player creates an avatar, using them to solve a series of brain teasers in single-player or multiplayer modes. The director, Kenta Kubo, designed it to be fun and enjoyable for his own family, adjusting the difficulty levels in classes to make it more suitable for all ages.

Big Brain Academy: Brain vs. Brain received mixed reviews from critics. It was praised for its presentation, multiplayer, and educational value, with criticism drawn for its limited gameplay offerings as a party game. It has sold over 1.94 million copies by December 2022, making it one of the best-selling games on the Nintendo Switch.