Benzphetamine

Benzphetamine
INN: Benzfetamine
Clinical data
Trade names	Didrex, others
Other names	Benzfetamine; d-Benzphetamine; (+)-Benzphetamine; (S)-(+)-Benzphetamine; (S)-Benzphetamine; (2S)-N-Benzyl-N-methylamphetamine; dextro-N-Benzyl-N-methylamphetamine; N-Benzyldextromethamphetamine; (+)-N-Benzyl-N,α-dimethylphenethylamine
AHFS/Drugs.com	Professional Drug Facts
License data	US DailyMed: Benzphetamine;
Dependence; liability	High
Routes of; administration	By mouth
ATC code	None;
Legal status
Legal status	AU: S4 (Prescription only); BR: Class F2 (Prohibited psychotropics); CA: Schedule I; DE: Anlage I (Authorized scientific use only); UK: Class C; US: Schedule III;
Pharmacokinetic data
Protein binding	75–99%
Metabolites	• Dextromethamphetamine; • Dextroamphetamine
Elimination half-life	4–6 hours
Identifiers
	IUPAC name (2S)-N-Benzyl-N-methyl-1-phenylpropan-2-amine;
CAS Number	156-08-1 ;
PubChem CID	5311017;
DrugBank	DB00865 ;
ChemSpider	4470556 ;
UNII	0M3S43XK27;
KEGG	D07514; D07515;
ChEBI	CHEBI:3044 ;
ChEMBL	ChEMBL3545985 ;
CompTox Dashboard (EPA)	DTXSID4022656 ;
Chemical and physical data
Formula	C17H21N
Molar mass	239.362 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES N(C)(Cc1ccccc1)[C@@H](C)Cc2ccccc2;
	InChI InChI=1S/C17H21N/c1-15(13-16-9-5-3-6-10-16)18(2)14-17-11-7-4-8-12-17/h3-12,15H,13-14H2,1-2H3/t15-/m0/s1 ; Key:YXKTVDFXDRQTKV-HNNXBMFYSA-N ;
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Benzphetamine, sold under the brand name Didrex among others, is an amphetamine-type stimulant and appetite suppressant used short-term for weight loss along with a doctor-approved, reduced-calorie diet, exercise, and behavioral program. It is prescribed for obesity to people who have been unable to lose weight through exercise and dieting alone. It is a prodrug of dextromethamphetamine and dextroamphetamine.