BRF1 (gene)

BRF1
Identifiers
Aliases	BRF1, BRF, BRF-1, GTF3B, HEL-S-76p, TAF3B2, TAF3C, TAFIII90, TF3B90, TFIIIB90, hBRF, CFDS, RNA polymerase III transcription initiation factor 90 kDa subunit, RNA polymerase III transcription initiation factor subunit, BRF1 RNA polymerase III transcription initiation factor subunit
External IDs	OMIM: 604902; MGI: 1919558; HomoloGene: 1161; GeneCards: BRF1; OMA:BRF1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	105,315,589 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	112,964,324 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; right uterine tube; ; right hemisphere of cerebellum; ; C1 segment; ; anterior pituitary; ; right frontal lobe; ; ventricular zone; ; ganglionic eminence; ; apex of heart; ; granulocyte;
	Top expressed in
	interventricular septum; ; neural layer of retina; ; lens; ; thymus; ; granulocyte; ; lip; ; otolith organ; ; utricle; ; spermatocyte; ; hand;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	TBP-class protein binding; metal ion binding; RNA polymerase III general transcription initiation factor activity; RNA polymerase III type 3 promoter sequence-specific DNA binding; transcription factor binding; protein binding; translation initiation factor activity;
Cellular component	transcription factor TFIIIB complex; nucleus; nucleoplasm;
Biological process	rRNA transcription; tRNA transcription; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of transcription by RNA polymerase III; transcription by RNA polymerase III; transcription initiation from RNA polymerase III promoter; transcription preinitiation complex assembly; DNA-templated transcription, initiation; RNA polymerase III preinitiation complex assembly; regulation of transcription by RNA polymerase III; translational initiation;
	Sources:Amigo / QuickGO
Orthologs
	2972
	72308
	ENSG00000185024
	ENSMUSG00000011158
	Q92994
	Q8CFK2
NM_001242786; NM_001242787; NM_001242788; NM_001242789; NM_001242790;
	NM_001519; NM_145685; NM_145696
	NM_028193
NP_001229715; NP_001229716; NP_001229717; NP_001229718; NP_001229719;
	NP_001510; NP_663718; NP_663718.1
	NP_082469
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor IIIB 90 kDa subunit is a protein that in humans is encoded by the BRF1 gene.