BCL11A

BCL11A
Identifiers
Aliases	BCL11A, BCL11A-L, BCL11A-S, BCL11A-XL, BCL11a-M, CTIP1, EVI9, HBFQTL5, ZNF856, B-cell CLL/lymphoma 11A, DILOS, B cell CLL/lymphoma 11A, BAF complex component, BAF chromatin remodeling complex subunit SMARCM1
External IDs	OMIM: 606557; MGI: 106190; HomoloGene: 11284; GeneCards: BCL11A; OMA:BCL11A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	60,554,467 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	24,174,123 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; primary visual cortex; ; Brodmann area 23; ; skin of hip; ; skin of thigh; ; middle temporal gyrus; ; postcentral gyrus; ; Region I of hippocampus proper; ; ventricular zone; ; superior frontal gyrus;
	Top expressed in
	Rostral migratory stream; ; barrel cortex; ; ganglionic eminence; ; piriform cortex; ; primary motor cortex; ; subiculum; ; medial ganglionic eminence; ; olfactory tubercle; ; subdivision of hippocampus; ; Region I of hippocampus proper;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; protein heterodimerization activity; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; protein kinase binding; sequence-specific DNA binding;
Cellular component	cytoplasm; nucleoplasm; nucleus; postsynaptic density;
Biological process	negative regulation of protein homooligomerization; negative regulation of neuron projection development; regulation of transcription, DNA-templated; regulation of dendrite development; negative regulation of transcription by RNA polymerase II; positive regulation of collateral sprouting; protein sumoylation; transcription, DNA-templated; negative regulation of collateral sprouting; positive regulation of neuron projection development; negative regulation of axon extension; signal transduction; positive regulation of transcription by RNA polymerase II; neurogenesis; negative regulation of dendrite development; positive regulation of gene expression; negative regulation of dendrite extension; negative regulation of neuron remodeling; cellular response to L-glutamate; negative regulation of branching morphogenesis of a nerve;
	Sources:Amigo / QuickGO
Orthologs
	53335
	14025
	ENSG00000119866
	ENSMUSG00000000861
	Q9H165
	Q9QYE3
NM_018014; NM_022893; NM_138553; NM_138559; NM_001363864;
	NM_001365609
	NM_001159289; NM_001159290; NM_001242934; NM_016707
	NP_060484; NP_075044; NP_612569; NP_001350793; NP_001352538
	NP_001152761; NP_001152762; NP_001229863; NP_057916
	Wikidata
View/Edit Human	View/Edit Mouse

B-cell lymphoma/leukemia 11A is a protein that in humans is encoded by the BCL11A gene.