BASP1

BASP1
Identifiers
Aliases	BASP1, CAP-23, CAP23, NAP-22, NAP22, brain abundant membrane attached signal protein 1
External IDs	OMIM: 605940; MGI: 1917600; HomoloGene: 38168; GeneCards: BASP1; OMA:BASP1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	17,276,843 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	25,413,850 bp
RNA expression pattern
	Top expressed in
	orbitofrontal cortex; ; middle temporal gyrus; ; frontal pole; ; Brodmann area 46; ; Brodmann area 23; ; Brodmann area 10; ; superior frontal gyrus; ; parietal lobe; ; postcentral gyrus; ; occipital lobe;
	Top expressed in
	perirhinal cortex; ; CA3 field; ; entorhinal cortex; ; retinal pigment epithelium; ; amygdala; ; cingulate gyrus; ; prefrontal cortex; ; barrel cortex; ; trigeminal ganglion; ; primary motor cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transcription corepressor activity; protein domain specific binding; protein binding;
Cellular component	cytoplasm; vesicle; nuclear speck; cell projection; membrane; growth cone; plasma membrane; cell junction; COP9 signalosome; extracellular exosome; cytoskeleton; nucleus;
Biological process	substantia nigra development; diaphragm development; positive regulation of metanephric ureteric bud development; positive regulation of heart growth; glomerular visceral epithelial cell differentiation; thorax and anterior abdomen determination; negative regulation of transcription, DNA-templated; gonad development; metanephric mesenchyme development; mesenchymal to epithelial transition;
	Sources:Amigo / QuickGO
Orthologs
	10409
	70350
	ENSG00000176788
	ENSMUSG00000045763
	P80723
	Q91XV3
	NM_006317; NM_001271606
	NM_027395
	NP_001258535; NP_006308
	NP_081671
	Wikidata
View/Edit Human	View/Edit Mouse

Brain acid soluble protein 1 is a protein that in humans is encoded by the BASP1 gene.

BASP1 (Brain acid soluble protein 1) is a 22Kd, N-terminal Myristoylated protein involved in gene regulation, cytoplasmic signaling in neurons, axon regeneration and a variety of other functions. BASP1 is encoded by the BASP1 gene and is part of the GMC protein family with GAP-43 and MARCKS. Although BASP1 has been mainly identified as a tumor suppressor, upregulation of BASP1 has been seen in several cancers and offers poor prognosis.