Arctigenin

(−)-Arctigenin
Names
	IUPAC name (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3- [(4-hydroxy-3-methoxyphenyl)methyl]-2-tetrahydrofuranone
Identifiers
CAS Number	7770-78-7 ;
3D model (JSmol)	Interactive image; Interactive image;
ChEMBL	ChEMBL435734 ;
ChemSpider	58506 ;
KEGG	C10545 ;
MeSH	arctigenin
PubChem CID	64981;
UNII	U76MR9VS6M ;
CompTox Dashboard (EPA)	DTXSID60998919 ;
	InChI InChI=1S/C21H24O6/c1-24-18-7-5-13(11-20(18)26-3)8-15-12-27-21(23)16(15)9-14-4-6-17(22)19(10-14)25-2/h4-7,10-11,15-16,22H,8-9,12H2,1-3H3/t15-,16+/m0/s1 Key: NQWVSMVXKMHKTF-JKSUJKDBSA-N ; InChI=1/C21H24O6/c1-24-18-7-5-13(11-20(18)26-3)8-15-12-27-21(23)16(15)9-14-4-6-17(22)19(10-14)25-2/h4-7,10-11,15-16,22H,8-9,12H2,1-3H3/t15-,16+/m0/s1 Key: NQWVSMVXKMHKTF-JKSUJKDBBB;
	SMILES COC1=C(C=C(C=C1)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC)OC; O=C2OC[C@H](Cc1cc(OC)c(OC)cc1)[C@H]2Cc3ccc(O)c(OC)c3;
Properties
Chemical formula	C21H24O6
Molar mass	372.41166
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Arctigenin is a lignan found in certain plants of the Asteraceae, including the greater burdock (Arctium lappa) and Saussurea heteromalla. It has shown antiviral and anticancer effects in vitro. It is the aglycone of arctiin.

The use of arctigenin has been shown to be effective in a mouse model of Japanese encephalitis.

It has been found to act as an agonist of adiponectin receptor 1 (AdipoR1).