Anemonin

Anemonin
Names
	IUPAC names trans-4,7-Dioxadispiro[4.0.46.25]dodeca-1,9-diene-3,8-dione; trans-1,7-Dioxadispiro[4.0.4.2]dodeca-3,9-diene-2,8-dione
Identifiers
CAS Number	508-44-1 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL1972777;
ChemSpider	10064 ;
PubChem CID	10496;
UNII	G99XG5B674 ;
CompTox Dashboard (EPA)	DTXSID70903913 ;
	InChI InChI=1S/C10H8O4/c11-7-1-3-9(13-7)5-6-10(9)4-2-8(12)14-10/h1-4H,5-6H2 Key: JLUQTCXCAFSSLD-UHFFFAOYSA-N ;
	SMILES C1CC2(C13C=CC(=O)O3)C=CC(=O)O2;
Properties
Chemical formula	C10H8O4
Molar mass	192.170 g·mol−1
Appearance	Colourless, odourless solid
Density	1.45g/cm3
Melting point	158 °C (316 °F; 431 K)
Boiling point	535.7 °C (996.3 °F; 808.9 K) @ 760mmHg
Solubility in water	low
Solubility in chloroform	very soluble
Hazards
Flash point	300.7 °C (573.3 °F; 573.8 K)
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	150 mg·kg−1 (mouse, IP)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Anemonin is a dibutenolide natural product found in members of the buttercup family (Ranunculaceae) such as Helleborus niger, Ranunculus bulbosus, R. ficaria, R. sardous, R. sceleratus, and Clematis hirsutissima. Originally isolated in 1792 by M. Heyer, It is the dimerization product of the toxin protoanemonin. One of the likely active agents in plants used in Chinese medicine as an anti-inflammatory and Native American medicine as a horse stimulant, its unique biological properties give it pharmaceutical potential as an anti-inflammatory agent.