Anatabine

Anatabine
Identifiers
	IUPAC name [2R,(+)]-1,2,3,6-Tetrahydro-2,3'-bipyridine;
CAS Number	581-49-7 ;
PubChem CID	11388;
ChemSpider	10910 ;
UNII	5PP654XB7D;
KEGG	C10126;
ChEBI	CHEBI:2705;
ChEMBL	ChEMBL3640772;
CompTox Dashboard (EPA)	DTXSID901016110 ;
Chemical and physical data
Formula	C10H12N2
Molar mass	160.220 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1cc(cnc1)[C@@H]2CC=CCN2;
	InChI InChI=1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h1-4,6,8,10,12H,5,7H2/t10-/m0/s1 ; Key:SOPPBXUYQGUQHE-JTQLQIEISA-N ;
	(verify)

Anatabine (uh-nat-uh-been,-bin) is one of the minor alkaloids found in plants in the family Solanaceae, which includes the tobacco plant and tomato. Commercial tobacco plants typically produce alkaloids at levels between 2% and 4% of total dry weight, with nicotine accounting for about 90% of the total alkaloid content, and the related compounds anatabine, nornicotine, and anabasine making up nearly all the rest. These compounds are thought to be biologically active, and part of plants' natural defense system against insects.

Anatabine has anti-inflammatory activity partly through inhibition of STAT3 phosphorylation in vitro and in vivo.