Actinidain

actinidain
Biological assembly image of actinidain from Actinidia chinensis. From PDB: 1AEC​.
Identifiers
EC no.3.4.22.14
CAS no.39279-27-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Actinidain (EC 3.4.22.14, actinidin, Actinidia anionic protease, proteinase A2 of Actinidia chinensis) is a type of cysteine protease enzyme found in fruits, including kiwifruit (genus Actinidia), pineapple, mango, banana, figs, and papaya. It is part of the peptidase C1 family of papain-like proteases.

Actinidain is an allergen in kiwifruit.

Actinidain is commercially used as a meat tenderizer and in coagulating milk for dairy products, like yogurt and cheese. The denaturation temperature of actinidain is 60 °C (140 °F), lower than that of similar meat tenderizing enzymes bromelain from pineapple and papain from papaya.